Journal of the American College of Surgeons
Volume 210, Issue 2 , Pages 140-147, February 2010

Clinical and Immunologic Responses of HLA-A3+ Breast Cancer Patients Vaccinated with the HER2/neu-Derived Peptide Vaccine, E75, in a Phase I/II Clinical Trial

  • Ritesh Patil, MD

      Affiliations

    • Joyce Murtha Breast Care Center, Windber Medical Center, Windber, PA
    • ,
  • Guy T. Clifton, MD

      Affiliations

    • Department of Surgery, Brooke Army Medical Center, Fort Sam Houston, TX
    • ,
  • Jarrod P. Holmes, MD

      Affiliations

    • Department of Hematology and Medical Oncology, Naval Medical Center, San Diego, CA
    • ,
  • Asna Amin, MD

      Affiliations

    • Cancer Vaccine Development Program, United States Military Cancer Institute, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD
    • ,
  • Mark G. Carmichael, MD

      Affiliations

    • Cancer Vaccine Development Program, United States Military Cancer Institute, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD
    • ,
  • Jeremy D. Gates, MD

      Affiliations

    • Department of Surgery, Brooke Army Medical Center, Fort Sam Houston, TX
    • ,
  • Linda H. Benavides, MD

      Affiliations

    • Department of Surgery, Brooke Army Medical Center, Fort Sam Houston, TX
    • ,
  • Matthew T. Hueman, MD

      Affiliations

    • Cancer Vaccine Development Program, United States Military Cancer Institute, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD
    • ,
  • Sathibalan Ponniah, PhD

      Affiliations

    • Cancer Vaccine Development Program, United States Military Cancer Institute, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD
    • ,
  • George E. Peoples, MD, FACS

      Affiliations

    • Department of Surgery, Brooke Army Medical Center, Fort Sam Houston, TX
    • Cancer Vaccine Development Program, United States Military Cancer Institute, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD
    • Corresponding Author InformationCorrespondence address: col George E Peoples, md, facs, Department of Surgery, General Surgery Service, Brooke Army Medical Center, 3851 Roger Brooke Dr, Fort Sam Houston, TX 78234

Received 26 August 2009; received in revised form 20 October 2009; accepted 21 October 2009. published online 21 December 2009.

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 Disclosure Information: Dr Peoples holds patent rights to the E75 vaccine.

 This study was supported by the United States Military Cancer Institute, Department of Surgery, Uniformed Services University of the Health Sciences, and the Department of Clinical Investigation, Walter Reed Army Medical Center, Bethesda, MD.

 This article represents the personal viewpoint of the authors and cannot be construed as a statement of official Department of the Army, Department of the Navy, or Department of Defense policy.

PII: S1072-7515(09)01557-9

doi:10.1016/j.jamcollsurg.2009.10.022

Journal of the American College of Surgeons
Volume 210, Issue 2 , Pages 140-147, February 2010

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