Journal of the American College of Surgeons
Volume 209, Issue 5 , Pages 603-607 , November 2009

Timing of Breast Cancer Treatments with Oocyte Retrieval and Embryo Cryopreservation

  • Jennifer Baynosa, MD

      Affiliations

    • Department of Surgery, Stanford University School of Medicine, Stanford, CA
  • ,
  • Lynn M. Westphal, MD, FACOG

      Affiliations

    • Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA
  • ,
  • Andrea Madrigrano, MD

      Affiliations

    • Department of Surgery, Stanford University School of Medicine, Stanford, CA
  • ,
  • Irene Wapnir, MD, FACS

      Affiliations

    • Department of Surgery, Stanford University School of Medicine, Stanford, CA
    • Corresponding Author InformationCorrespondence address: Irene Wapnir, MD, Department of Surgery, Stanford University School of Medicine, 300 Pasteur Dr H3625, Stanford, CA 94305

Received 11 May 2009 ,Revised 1 July 2009 ,Accepted 7 August 2009.

References 

  1. American Cancer Society. Breast cancer facts and figures 2007–2008. Atlanta: American Cancer Society, Inc.
  2. Goldhirsch A, Gelber RD, Yothers G, et al. Adjuvant therapy for very young women with breast cancer: need for tailored treatments. J Natl Cancer Inst Monogr. 2001;44–51
  3. Kroman N, Jensen MB, Wohlfahrt J, et al. Factors influencing the effect of age on prognosis in breast cancer: population based study. BMJ. 2000;320:474–478
  4. Early Breast Cancer Trials Collaborative Group. Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomized trials. Lancet. 2005;365:1687–1717
  5. Gnerlich J, Deshpande A, Jeffe D, et al. Elevated breast cancer mortality in women younger than age 40 years compared with older women is attributed to poorer survival in early-stage disease. J Am Coll Surg. 2009;208:341–347
  6. Minton SE, Munster PN. Chemotherapy induced amenorrhea and fertility in women undergoing adjuvant treatment for breast cancer. Cancer Control. 2002;9:466–472
  7. Walshe JM, Denduluri N, Swain SM. Amenorrhea in premenopausal women after adjuvant chemotherapy for breast cancer. J Clin Oncol. 2006;24:5769–5779
  8. Partridge AH, Gelber S, Peppercorn J, et al. Web-based survey of fertility issues in young women with breast cancer. J Clin Oncol. 2004;22:4174–4183
  9. Partridge AH, Gelber S, Peppercorn J, et al. Fertility and menopausal outcomes in young breast cancer survivors. Clin Breast Cancer. 2008;8:65–69
  10. Swain S, Land S, Ritter M, et al. Amenorrhea in premenopausal women on the doxorubicin-cyclophosphamide-followed-by-docetaxel arm of NSABP B-30 trial. Breast Cancer Res Treat. 2009;113:315–320
  11. Trounson A, Mohr L. Human pregnancy following cryopreservation, thawing and transfer of an eight-cell embryo. Nature. 1983;305:707–709
  12. Oktay K, Buyuk E, Davis O, et al. Fertility preservation in breast cancer patients: IVF and embryo cryopreservation after ovarian stimulation with tamoxifen. Hum Rep. 2003;18:90–95
  13. Oktay K, Cil AP, Bang H. Efficiency of oocyte cryopreservation: a meta-analysis. Fertil Steril. 2006;86:70–80
  14. Oktay K, Karlikaya G. Ovarian function after transplantation of frozen, banked autologous ovarian tissue. N Engl J Med. 2000;342:1919
  15. Meirow D, Levron J, Eldar-Geva T, et al. Pregnancy after transplantation of cryopreserved ovarian tissue in a patient with ovarian failure after chemotherapy. N Engl J Med. 2005;353:318–321
  16. Sonmezer M, Oktay K. Fertility preservation in young women undergoing breast cancer therapy. Oncologist. 2006;11:422–434
  17. Oktay K, Hourvitz A, Shain G, et al. Letrozole reduces estrogen and gonadotropin exposure in women with breast cancer undergoing ovarian stimulation before chemotherapy. J Clin Endocrinol Metab. 2006;91:3885–3890
  18. Oktay K, Buyuk E, Lebertella N, et al. Fertility preservation in breast cancer patients: a prospective controlled comparison of ovarian stimulation with tamoxifen and letrozole for embryo cryopreservation. J Clin Oncol. 2005;23:4347–4353
  19. Madrigrano A, Westphal L, Wapnir I. Egg retrieval with cryopreservation does not delay breast cancer treatment. Am J Surg. 2007;194:477–481
  20. Lohrisch C, Pailtel C, Gelmon K, et al. Impact on survival of time from definitive surgery to initiation of adjuvant chemotherapy for early-stage breast cancer. J Clin Oncol. 2006;24:4888–4894
  21. Jara Sanchez C, Ruiz A, Martin M, et al. Influence of timing of initiation of adjuvant chemotherapy over survival in breast cancer: a negative outcome study by the Spanish breast cancer research group (GEICAM). Breast Cancer Res Treat. 2007;101:215–223
  22. Cold S, During M, Ewertz M, et al. Does timing of adjuvant chemotherapy influence the prognosis after early breast cancer? (Results of the Danish Breast Cancer Cooperative Group (DBCG)). Br J Cancer. 2005;93:627–632
  23. Platet N, Cathiard AM, Gleizes M, Garcia M. Estrogens and their receptors in breast cancer progression: a dual role in cancer proliferation and invasion. Crit Rev Oncol Hematol. 2004;51:55–67
  24. Azim AA, Costantini-Ferrando M, Oktay K. Safety of fertility preservation by ovarian stimulation with letrozole and gonadotropins in patients with breast cancer: a prospective controlled study. J Clin Oncol. 2008;26:2630–2635
  25. Wohlfahrt J, Anderson PK, Mourodsen HT, et al. Risk of late stage breast cancer after a childbirth. Am J Epidemiol. 2001;153:1079–1084
  26. Del Mastro L, Catzeddu T, Venturini M. Infertility and pregnancy after breast cancer: current knowledge and future perspectives. Cancer Treat Rev. 2006;32:417–422
  27. Kroman N, Mouridsen HT. Prognostic influence of pregnancy before, around, and after diagnosis of breast cancer. Breast. 2003;12:516–521
  28. Blakely LJ, Buzdar AU, Lozada JA, et al. Effects of pregnancy after treatment for breast carcinoma on survival and risk of recurrence. Cancer. 2004;100:465–469
  29. Gelber S, Coates AS, Goldhirsch A, et al. Effect of pregnancy on overall survival after the diagnosis of early-stage breast cancer. J Clin Oncol. 2001;19:1671–1675
  30. Fisher B, Ravdin RG, Ausman RK, et al. Surgical adjuvant chemotherapy in cancer of the breast: results of a decade of cooperative investigation. Ann Surg. 1968;168:337–356
  31. Meirow D, Nugent D. The effects of radiotherapy and chemotherapy on female reproduction. Hum Reprod Update. 2001;7:535–543
  32. Bines J, Oleske DM, Colbeigh MA. Ovarian function in premenopausal women treated with adjuvant chemotherapy for breast cancer. J Clin Oncol. 1996;14:1718–1729
  33. Goldhirsch A, Gelber RD, Castiglione M. The magnitude of endocrine effects of adjuvant chemotherapy for premenopausal breast cancer patients (The International Breast Cancer Study Group). Ann Oncol. 1990;1:183–188
  34. Sanders JE, Buckner CD, Amos S, et al. Ovarian function following marrow transplantation for aplastic anemia or leukemia. J Clin Oncol. 1988;6:813–818
  35. Cance WG, Carey LA, Calvo BF, et al. Long-term outcome of neoadjuvant therapy for locally advanced breast carcinoma: effective clinical downstaging allows breast preservation and predicts outstanding local control and survival. Ann Surg. 2002;236:295–302discussion 302–303
  36. Connell S, Patterson C, Newman B. A qualitative analysis of reproductive issues raised by young Australian women with breast cancer. Health Care Women Int. 2006;27:94–110
  37. Brinsden PR. Gestational surrogacy. Human Reprod Update. 2003;9:483–491

 Disclosure Information: Nothing to disclose.

 Supported by the INBRE program of the National Center for Research Resources NIH grant # P20 RR-016464, and the Susan G Komen for the Cure interdisciplinary breast fellowship grant IBF-2006-04 for the funding of Jennifer Baynosa and Andrea Madrigrano.

PII: S1072-7515(09)01215-0

doi: 10.1016/j.jamcollsurg.2009.08.006

Journal of the American College of Surgeons
Volume 209, Issue 5 , Pages 603-607 , November 2009