Journal of the American College of Surgeons
Volume 209, Issue 5 , Pages 589-594 , November 2009

Fondaparinux for Prevention of Venous Thromboembolism in High-Risk Trauma Patients: A Pilot Study

Received 16 June 2009 ,Revised 30 July 2009 ,Accepted 4 August 2009.

References 

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  2. Meissner MH, Chandler WL, Elliott JS. Venous thromboembolism in trauma: a local manifestation of systemic hypercoagulability?. J Trauma. 2003;54:224–231
  3. Bendinelli C, Balogh Z. Postinjury thromboprophylaxis. Curr Opin Crit Care. 2008;14:673–678
  4. Eriksson BI, Bauer KA, Lassein MR, Turpie AG. Fondaparinux compared with enoxaparin for the prevention of venous thromboembolism after hip-fracture surgery. N Engl J Med. 2001;345:1298–1304
  5. Bauer KA, Eriksson BI, Lassen MR, Turpie AG. Fondaparinux compared with enoxaparin for the prevention of venous thromboembolism after elective major knee surgery. N Engl J Med. 2001;345:1305–1310
  6. Turpie AG, Gallus AS, Hoek JA. A synthetic pentasaccharide for the prevention of deep-vein thrombosis after total hip replacement. N Engl J Med. 2001;344:619–625
  7. Turpie AG, Bauer KA, Eriksson BI, Lassen MR. Superiority of fondaparinux over enoxaparin in preventing venous thromboembolism in major orthopedic surgery using different efficacy end points. Chest. 2004;126:501–508
  8. Agnelli G, Bergqvist D, Cohen AT, et al. Randomized clinical trial of postoperative fondaparinux versus perioperative dalteparin for prevention of venous thromboembolism in high-risk abdominal surgery. Br J Surg. 2005;92:1212–1220
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  16. Rutherford EJ, Schooler WG, Sredzienski E, et al. Optimal dose of enoxaparin in critically ill trauma and surgical patients. J Trauma. 2005;58:1167–1170
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 Disclosure Information: Dr Knudson has received salary support as a study coordinator and vascular technician from GlaxoSmithKline Pharmaceuticals, which also supplied the drug for the study. All other authors have nothing to disclose.

PII: S1072-7515(09)01207-1

doi: 10.1016/j.jamcollsurg.2009.08.001

Journal of the American College of Surgeons
Volume 209, Issue 5 , Pages 589-594 , November 2009

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