Journal of the American College of Surgeons
Volume 209, Issue 5 , Pages 608-613 , November 2009

Attaining Negative Margins in Breast-Conservation Operations: Is There a Consensus among Breast Surgeons?

  • Sarah L. Blair, MD, FACS

      Affiliations

    • University of California San Diego, Moores Cancer Center, La Jolla, CA
    • Corresponding Author InformationCorrespondence address: Sarah Blair, MD, University of California San Diego, Moores Cancer Center, 3855 Health Sciences Dr #0987, La Jolla, CA 92093-0987
    • ,
  • Kari Thompson, MD

      Affiliations

    • Department of Surgery, University of California San Diego, La Jolla, CA
    • ,
  • Joseph Rococco, MD

      Affiliations

    • Department of Surgery, State University of New York Health Science Center at Syracuse, Syracuse, NY
    • ,
  • Vanessa Malcarne, PhD

      Affiliations

    • Department of Psychology, San Diego State University, San Diego, CA
    • ,
  • Peter D. Beitsch, MD, FACS

      Affiliations

    • Dallas Surgical Group, Dallas, TX
    • ,
  • David W. Ollila, MD, FACS

      Affiliations

    • Department of Surgery, University of North Carolina Chapel Hill, Chapel Hill, NC

Received 22 May 2009 ,Revised 24 July 2009 ,Accepted 27 July 2009.

References 

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  2. van Dongen JA, Bartelink H, Fentiman IS, et al. Factors influencing local relapse and survival and results of salvage treatment after breast-conserving therapy in operable breast cancer: EORTC trial 10801, breast conservation compared with mastectomy in TNM stage I and II breast cancer. Eur J Cancer. 1992;28A:801–805
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  11. Taghian A, Jagsi R, Makris A, et al. Results of a survey regarding irradiation of internal mammary chain in patients with breast cancer: practice is culture driven rather than evidence based. Int J Radiat Oncol Biol Phys. 2004;60:706–714
  12. Muttalib M, Tisdall M, Scawn R, et al. Intra-operative specimen analysis using faxitron microradiography for excision of mammographically suspicious, non-palpable breast lesions. Breast. 2004;13:307–315
  13. Fisher B, Anderson S, Redmond CK, et al. Reanalysis and results after 12 years of follow-up in a randomized clinical trial comparing total mastectomy with lumpectomy with or without irradiation in the treatment of breast cancer. N Engl J Med. 1995;333:1456–1461
  14. Gorechlad JW, McCabe EB, Higgins JH, et al. Screening for recurrences in patients treated with breast-conserving surgery: is there a role for MRI?. Ann Surg Oncol. 2008;15:1703–1709
  15. Early Breast Cancer Trialists' Collaborative Group (EBCTCG). Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. Lancet. 2005;365:1687–1717
  16. Jacobson AF, Asad J, Boolbol SK, et al. Do additional shaved margins at the time of lumpectomy eliminate the need for re-excision?. Am J Surg. 2008;196:556–558
  17. Cao D, Lin C, Woo SH, et al. Separate cavity margin sampling at the time of initial breast lumpectomy significantly reduces the need for reexcisions. Am J Surg Pathol. 2005;29:1625–1632
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 Disclosure Information: Nothing to disclose.

 This research was supported by a grant from the Department of Defense Idea Grant W81XWH-06-1-052.

PII: S1072-7515(09)01206-X

doi: 10.1016/j.jamcollsurg.2009.07.026

Journal of the American College of Surgeons
Volume 209, Issue 5 , Pages 608-613 , November 2009

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