Journal of the American College of Surgeons
Volume 209, Issue 1 , Pages 68-74 , July 2009

A Phase 3b, Open-Label, Single-Group Immunogenicity and Safety Study of Topical Recombinant Thrombin in Surgical Hemostasis

  • Neil K. Singla, MD

      Affiliations

    • Lotus Clinical Research, Huntington Memorial Hospital, Pasadena, CA
    • ,
  • Jeffrey L. Ballard, MD, FACS

      Affiliations

    • Vascular and Interventional Specialists of Orange County, Inc, Orange, CA
    • ,
  • Gregory Moneta, MD, FACS

      Affiliations

    • Oregon Health and Science University, Portland, OR
    • ,
  • C. Duane Randleman Jr, MD

      Affiliations

    • Cardio Thoracic Surgeons, PC, Birmingham, AL
    • ,
  • Kenneth L. Renkens, MD, FACS

      Affiliations

    • Indiana Spine Group, Indianapolis, IN
    • ,
  • W. Allan Alexander, MD

      Affiliations

    • ZymoGenetics, Inc, Seattle, WA
    • Corresponding Author InformationCorrespondence address: W Allan Alexander, MD, ZymoGenetics, Inc, 1201 Eastlake Ave E, Seattle, WA 98102

Received 4 February 2009 ,Revised 4 February 2009 ,Accepted 9 March 2009.

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 Disclosure Information: The clinical study was funded by ZymoGenetics, Inc. Dr Alexander is employed by ZymoGenetics, Inc as medical director, and the remaining authors were clinical investigators for this study.

 The ClinicalTrials.gov identifier for this study is NCT00491608.

PII: S1072-7515(09)00325-1

doi: 10.1016/j.jamcollsurg.2009.03.016

Journal of the American College of Surgeons
Volume 209, Issue 1 , Pages 68-74 , July 2009

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