Journal of the American College of Surgeons
Volume 207, Issue 2 , Pages 191-196 , August 2008

Elastic Fiber Depletion in the Supporting Ligaments of the Gastroesophageal Junction: A Structural Basis for the Development of Hiatal Hernia

  • John A. Curci, MD, FACS

      Affiliations

    • Washington University Institute for Minimally Invasive Surgery and the Department of Surgery, Washington University School of Medicine, St Louis, MO
    • Corresponding Author InformationCorrespondence address: John A Curci, MD, FACS, Department of Surgery, Washington University School of Medicine, 660 S Euclid Ave, Campus Box 8109, St Louis, MO 63110.
    • ,
  • Lora M. Melman, MD

      Affiliations

    • Washington University Institute for Minimally Invasive Surgery and the Department of Surgery, Washington University School of Medicine, St Louis, MO
    • ,
  • Robert W. Thompson, MD, FACS

      Affiliations

    • Washington University Institute for Minimally Invasive Surgery and the Department of Surgery, Washington University School of Medicine, St Louis, MO
    • Department of Radiology, Washington University School of Medicine, St Louis, MO
    • Department of Cell Biology and Physiology, Washington University School of Medicine, St Louis, MO
    • ,
  • Nathaniel J. Soper, MD, FACS

      Affiliations

    • Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL.
    • ,
  • Brent D. Matthews, MD, FACS

      Affiliations

    • Washington University Institute for Minimally Invasive Surgery and the Department of Surgery, Washington University School of Medicine, St Louis, MO

Received 4 December 2007 ,Revised 26 February 2008 ,Accepted 26 February 2008.

References 

  1. Gangopadhyay N, Perrone JM, Soper NJ, et al. Outcomes of laparoscopic paraesophageal hernia repair in elderly and high-risk patients. Surgery. 2006;140:491–499
  2. Christensen J, Miftakhov R. Hiatus hernia: a review of evidence for its origin in esophageal longitudinal muscle dysfunction. Am J Med. 2000;108:3S–7S
  3. DeMeester TR, Lafontaine E, Joelsson BE, et al. Relationship of a hiatal hernia to the function of the body of the esophagus and the gastroesophageal junction. J Thorac Cardiovasc Surg. 1981;82:547–558
  4. Kahrilas PJ. The role of hiatus hernia in GERD. Yale J Biol Med. 1999;72:101–111
  5. Kahrilas PJ, Wu S, Lin S, Pouderoux P. Attenuation of esophageal shortening during peristalsis with hiatus hernia. Gastroenterology. 1995;109:1818–1825
  6. Laimer E. Beitrag zur Anatomie des Oesophagus. Wien Med Jahrbucher. 1883;333–388
  7. Strasberg SM, Silver MD. The phrenoesophageal membrane. Surg Forum. 1968;19:294–296
  8. Kremer B, Menck J, Lierse W. Phrenico-esophageal membrane: anchoring of the terminal esophagus and cardia at the diaphragm. Langenbecks Arch Chir. 1987;371:59–67
  9. Kwok H, Marriz Y, Al-Ali S, Windsor JA. Phrenoesophageal ligament re-visited. Clin Anat. 1999;12:164–170
  10. Jansen PL, Mertens Pr P, Klinge U, Schumpelick V. The biology of hernia formation. Surgery. 2004;136:1–4
  11. Parks WC, Pierce RA, Lee KA, Mecham RP. Elastin. In:  Kleinman HK editors. Advances in molecular cell biology. Greenwich, CT: JAI Press; 1993;p. 133–182
  12. Campa JS, Greenhalgh RM, Powell JT. Elastin degradation in abdominal aortic aneurysms. Atherosclerosis. 1987;65:13–21
  13. Shapiro SD. Elastolytic metalloproteinases produced by human mononuclear phagocytes (Potential roles in destructive lung disease). Am J Respir Crit Care Med. 1994;150:S160–S164
  14. Starcher B, Conrad M. A role for neutrophil elastase in solar elastosis. Ciba Found Symp. 1995;192:338–346discussion 337–346
  15. Crescenzi A, Muda AO, Origgi P, et al. Physico-chemical analysis of resorcin-fuchsin reagents and its relevance to staining quality of elastic fibres. Eur J Basic Appl Histochem. 1991;35:37–44
  16. El Sherif A, Yano F, Mittal S, Filipi CJ. Collagen metabolism and recurrent hiatal hernia: cause and effect?. Hernia. 2006;10:511–520
  17. Zheng H, Si Z, Kasperk R, et al. Recurrent inguinal hernia: disease of the collagen matrix?. World J Surg. 2002;26:401–408

 Disclosure Information: Nothing to disclose.

PII: S1072-7515(08)00288-3

doi: 10.1016/j.jamcollsurg.2008.02.036

Journal of the American College of Surgeons
Volume 207, Issue 2 , Pages 191-196 , August 2008

Article Tools

* Image Usage & Resolution