Journal of the American College of Surgeons
Volume 203, Issue 4 , Pages 539-545 , October 2006

Obesity Increases Risk of Organ Failure after Severe Trauma

Presented at the 36th Meeting of the Western Trauma Association, Big Sky, MT, February 2006.

  • David J. Ciesla, MD

      Affiliations

    • Department of Surgery, Washington Hospital Center, Washington, DC
    • Corresponding Author InformationCorrespondence address: David J Ciesla, MD, Department of Surgery, Washington Hospital Center, 110 Irving St NW Suite 4B-39, Washington, DC 20005.
    • ,
  • Ernest E. Moore, MD, FACS

      Affiliations

    • Department of Surgery, Denver Health Medical Center, and the University of Colorado Health Sciences Center, Denver, CO.
    • ,
  • Jeffery L. Johnson, MD, FACS

      Affiliations

    • Department of Surgery, Denver Health Medical Center, and the University of Colorado Health Sciences Center, Denver, CO.
    • ,
  • Jon M. Burch, MD, FACS

      Affiliations

    • Department of Surgery, Denver Health Medical Center, and the University of Colorado Health Sciences Center, Denver, CO.
    • ,
  • C. Clay Cothren, MD, FACS

      Affiliations

    • Department of Surgery, Denver Health Medical Center, and the University of Colorado Health Sciences Center, Denver, CO.
    • ,
  • Angela Sauaia, MD, PhD

      Affiliations

    • Department of Surgery, Denver Health Medical Center, and the University of Colorado Health Sciences Center, Denver, CO.

Received 27 March 2006 ,Revised 26 June 2006 ,Accepted 28 June 2006.

References 

  1. Mokdad AH , Ford ES , Bowman BA , et al.   Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001 . JAMA . 2003;289:76–79
  2. Flegal KM , Graubard BI , Williamson DF , Gail MH . Excess deaths associated with underweight, overweight, and obesity . JAMA . 2005;293:1861–1867
  3. Lyon CJ , Law RE , Hsueh WA . Minireview: adiposity, inflammation, and atherogenesis . Endocrinology . 2003;144:2195–2200
  4. Moore EE , Moore FA . Postinjury multiple organ failure . In:  Moore EE ,  Fleciano DV ,  Mattox KL editor. Trauma . 5th ed.. New York: McGraw-Hill; 2004;p. 1397–1423
  5. Calvet HM , Yoshikawa TT . Infections in diabetes . Infect Dis Clin North Am . 2001;15:407–421 , viii
  6. Ciesla DJ , Moore EE , Johnson JL , et al.   A 12-year prospective study of postinjury multiple organ failure: has anything changed? . Arch Surg . 2005;140:432–438 discussion 438–440
  7. Ciesla DJ , Moore EE , Johnson JL , et al.   Multiple organ dysfunction during resuscitation is not postinjury multiple organ failure . Arch Surg . 2004;139:590–594 discussion 594–595
  8. Moore FA , Moore EE , Sauaia A . Blood transfusion (An independent risk factor for postinjury multiple organ failure) . Arch Surg . 1997;132:620–624 discussion 624–625
  9. Sauaia A , Moore FA , Moore EE , et al.   Early predictors of postinjury multiple organ failure . Arch Surg . 1994;129:39–45
  10. Quesenberry CP , Caan B , Jacobson A . Obesity, health services use, and health care costs among members of a health maintenance organization . Arch Intern Med . 1998;158:466–472
  11. Flegal KM , Carroll MD , Ogden CL , Johnson CL . Prevalence and trends in obesity among US adults, 1999–2000 . JAMA . 2002;288:1723–1727
  12. Brown CV , Neville AL , Rhee P , et al.   The impact of obesity on the outcomes of 1,153 critically injured blunt trauma patients . J Trauma . 2005;59:1048–1051 discussion 1051
  13. Arbabi S , Wahl WL , Hemmila MR , et al.   The cushion effect . J Trauma . 2003;54:1090–1093
  14. Byrnes MC , McDaniel MD , Moore MB , et al.   The effect of obesity on outcomes among injured patients . J Trauma . 2005;58:232–237
  15. Bertakis KD , Azari R . Obesity and the use of health care services . Obes Res . 2005;13:372–379
  16. Buntin MB , Garten AD , Paddock S , et al.   How much is postacute care use affected by its availability? . Health Serv Res . 2005;40:413–434
  17. Neville AL , Brown CV , Weng J , et al.   Obesity is an independent risk factor of mortality in severely injured blunt trauma patients . Arch Surg . 2004;139:983–987
  18. Brown CV , Neville AL , Salim A , et al.   The impact of obesity on severely injured children and adolescents . J Pediatr Surg . 2006;41:88–91 discussion 88–91
  19. Choban PS , Weireter LJ , Maynes C . Obesity and increased mortality in blunt trauma . J Trauma . 1991;31:1253–1257

 Competing Interests Declared: None.Supported in part by NIH grants P50GM49222, T32GM08315, U546M62119, Jourdan Block Trauma Foundation.

PII: S1072-7515(06)01083-0

doi: 10.1016/j.jamcollsurg.2006.06.029

Journal of the American College of Surgeons
Volume 203, Issue 4 , Pages 539-545 , October 2006

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