Journal of the American College of Surgeons
Volume 203, Issue 5 , Pages 585-598.e1, November 2006

Molecular Diagnostics in Sepsis: From Bedside to Bench

  • T. Philip Chung, MD

      Affiliations

    • Department of Surgery, School of Medicine, Washington University, St Louis
    • ,
  • Jason M. Laramie, MS

      Affiliations

    • Department of Surgery, School of Medicine, Washington University, St Louis
    • Mr. Laramie’s current affiliation is Bioinformatics and Systems Biology Program, Boston University, Boston, MA.
    • ,
  • Donald J. Meyer, MS

      Affiliations

    • Partek Incorporated, St Charles, MO.
    • TD, DJM, and HD are employees of Partek Incorporated, a software company with expertise in microarray analyses, for example, nested cross-validation. GeneChip analyses were performed using Partek software as described herein; there were no monetary contributions.
    • ,
  • Thomas Downey, MS

      Affiliations

    • Partek Incorporated, St Charles, MO.
    • TD, DJM, and HD are employees of Partek Incorporated, a software company with expertise in microarray analyses, for example, nested cross-validation. GeneChip analyses were performed using Partek software as described herein; there were no monetary contributions.
    • ,
  • Laurence H.Y. Tam, MS

      Affiliations

    • Department of Surgery, School of Medicine, Washington University, St Louis
    • ,
  • Huashi Ding, MS

      Affiliations

    • Partek Incorporated, St Charles, MO.
    • TD, DJM, and HD are employees of Partek Incorporated, a software company with expertise in microarray analyses, for example, nested cross-validation. GeneChip analyses were performed using Partek software as described herein; there were no monetary contributions.
    • ,
  • Timothy G. Buchman, PhD, MD, FACS

      Affiliations

    • Department of Surgery, School of Medicine, Washington University, St Louis
    • Department of Medicine, School of Medicine, Washington University, St Louis
    • Department of Anesthesiology, School of Medicine, Washington University, St Louis
    • ,
  • Irene Karl, PhD

      Affiliations

    • Department of Medicine, School of Medicine, Washington University, St Louis
    • ,
  • Gary D. Stormo, PhD

      Affiliations

    • Department of Genetics, School of Medicine, Washington University, St Louis
    • ,
  • Richard S. Hotchkiss, MD

      Affiliations

    • Department of Surgery, School of Medicine, Washington University, St Louis
    • Department of Anesthesiology, School of Medicine, Washington University, St Louis
    • ,
  • J. Perren Cobb, MD, FACS

      Affiliations

    • Department of Surgery, School of Medicine, Washington University, St Louis
    • Corresponding Author InformationCorrespondences address: J Perren Cobb, MD, FACS, Department of Surgery, School of Medicine, Washington University, Campus Box 8109, 660 South Euclid Ave, St Louis, MO 63110.

Received 11 May 2006; received in revised form 12 June 2006; accepted 28 June 2006. published online 08 September 2006.

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 Competing Interests Declared: Design and conduct of the study and collection, management, analysis, and interpretation of data were supported, in part, by GM59960 (JPC), GM59960-02S1 (JPC), GM44118 (RSH), and the American College of Surgeons George HA Clowes Jr Memorial Research Career Development Award (JPC). The funding agencies did not conduct any portion of the study and did not contribute to manuscript preparation.

PII: S1072-7515(06)01082-9

doi:10.1016/j.jamcollsurg.2006.06.028

Journal of the American College of Surgeons
Volume 203, Issue 5 , Pages 585-598.e1, November 2006

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