Journal of the American College of Surgeons
Volume 199, Issue 3 , Pages 411-418 , September 2004

Gene expression after crush injury of human saphenous vein: Using microarrays to define the transcriptional profile1

Abstract presented at the American College of Surgeons 89th Annual Clinical Congress, Surgical Forum, Chicago, IL, October 2003.

  • Ray M. Price, PhD

      Affiliations

    • Department of Surgery, Morristown Memorial Hospital, Atlantic Health System, Morristown, NJ, USA
    • ,
  • Nirman Tulsyan, MD

      Affiliations

    • Department of Surgery, Morristown Memorial Hospital, Atlantic Health System, Morristown, NJ, USA
    • ,
  • James J. Dermody, PhD (FACMC)

      Affiliations

    • Center for Human and Molecular Genetics, UMDNJ—the University of Medicine and Dentistry of New Jersey, Newark, NJ, USA
    • Department of Microbiology and Molecular Genetics, UMDNJ—the University of Medicine and Dentistry of New Jersey, Newark, NJ, USA
    • ,
  • Marvin Schwalb, PhD

      Affiliations

    • Center for Human and Molecular Genetics, UMDNJ—the University of Medicine and Dentistry of New Jersey, Newark, NJ, USA
    • Department of Microbiology and Molecular Genetics, UMDNJ—the University of Medicine and Dentistry of New Jersey, Newark, NJ, USA
    • ,
  • Patricia Soteropoulos, PhD

      Affiliations

    • Center for Applied Genomics, Public Health Research Institute, Newark, NJ, USA
    • Department of Microbiology and Molecular Genetics, UMDNJ—the University of Medicine and Dentistry of New Jersey, Newark, NJ, USA
    • ,
  • John J. Castronuovo Jr, MD (FACS)

      Affiliations

    • Department of Surgery, Morristown Memorial Hospital, Atlantic Health System, Morristown, NJ, USA
    • Corresponding Author InformationCorrespondence address: John J Castronuovo Jr, MD, Department of Surgery, Morristown Memorial Hospital, Atlantic Health System, 100 Madison Ave, Morristown, NJ 07962-1956 USA

Received 30 December 2003 ,Revised 2 April 2004 ,Accepted 29 April 2004.

References 

  1. Castronuovo JJ, Smith TJ, Price RM. Validation of an in vitro model of human saphenous vein hyperplasia. J Vasc Surg. 2002;35:152–157
  2. Clowes AW, Reidy MA, Clowes MM. Mechanisms of stenosis after arterial injury. Lab Invest. 1983;49:208–215
  3. Castronuovo JJ, Price RM. The sequence of gene expression in cultured human saphenous vein after injury. J Vasc Surg. 2002;35:146–151
  4. Brazma A, Hingamp P, Quackenbush J, et al.  Minimum information about a microarray experiment (MIAME)—toward standards for microarray data. Nat Genet. 2001;29:365–371 Available at: http://www.mged.org/Workgroups/MIAME/miame.html. Accessed June 20, 2004
  5. Miller CJ, Hey Y, Pepper S. Conforming to MIAME—a guide to prospective authors of Affymetrix-based microarray papers. 2004; Available at: http://bioinf.picr.man.ac.uk/mbcf/miame_ma.shtml. Accessed June 20,
  6. NetAffx Analysis Center, Affymetrix, 2003. Available at: http://www.affymetrix.com/analysis/index.affx. Accessed June 20, 2004
  7. Aris V, Recce M. A method to improve detection of disease using selectively expressed genes in microarray data. In: Methods of microarray data analysis. Dordrecht: Kluwer Academic; 2002;p. 69–81
  8. Rebhan M, Chalifa-Caspi V, Prilusky J, Lancet D. GeneCards (encyclopedia for genes, proteins and diseases). Rehovot, Israel: Weizmann Institute of Science, Bioinformatics Unit and Genome Center; 1997; Available at: http://bioinformatics.weizmann.ac.il/cards. Accessed June 20, 2004
  9. Eisen MB, Spellman PT, Brown PO, Botstein D. Cluster analysis and display of genome-wide expression patterns. Proc Natl Acad Sci USA. 1998;95:14863–14868
  10. Price RM, Tulsyan N, Dermody J, et al.  Human gene microarray suggests a set of genes that characterize the response to injury of saphenous vein. J Am Coll Surg. 2002;195:S105
  11. He X, Saint-Jeannet JP, Wang Y, et al.  A member of the Frizzled protein family mediating axis induction by Wnt-5A. Science. 1997;275:1652–1654
  12. Kuhl M, Sheldahl LC, Park M, et al.  The Wnt/Ca2+ pathway (A new vertebrate Wnt signaling pathway takes shape). Trends Genet. 2000;16:279–283
  13. Kawano Y, Kypta R. Secreted antagonists of the Wnt signaling pathway. J Cell Sci. 2003;116:2627–2634
  14. Mao C, Malek OT-B, Pueyo ME, et al.  Differential expression of rat frizzled-related frzb-1 and frizzled receptor fz1 and fz2 genes in the rat aorta after balloon injury. Arterioscler Thromb Vasc Biol. 2000;20:43–51
  15. Mao B, Wu W, Davidson G, et al.  Kremen proteins are Dickkopf receptors that regulate Wnt/β-catenin signalling. Nature. 2002;417:664–667
  16. Wang X, Xiao Y, Mou Y, et al.  A role for the β-catenin/T cell factor signaling cascade in vascular remodeling. Circ Res. 2002;90:340–347
  17. Xu L, Corcoran RB, Welsh JW, et al.  WISP1 is a Wnt-1-and β-catenin-responsive oncogene. Genes Develop. 2000;14:585–595
  18. Crean JK, Lappin D, Godson C, Brady HR. Connective tissue growth factor (an attractive therapeutic target in fibrotic renal disease). Expert Opin Ther Targets. 2001;5:519–530
  19. Brigstock DR. The CCN family (a new stimulus package). J Endocrinol. 2003;178:169–175
  20. Boheler KR, Schwartz K. Gene expression in cardiac hypertrophy. Trends Cardiovasc Med. 1992;2:176–182
  21. Huelsken J, Behrens J. The Wnt signalling pathway. J Cell Sci. 2002;115:3977–3978
  22. van Gijn ME, Daemen JAP, Smits JFM, Blankensteijn WM. The wnt-frizzled cascade in cardiovascular disease. Cardiovasc Res. 2002;55:16–24
  23. Moon RT, Brown JD, Torres M. WNTs modulate cell fate and behavior during vertebrate development. Trends Genet. 1997;13:157–162
  24. Sanoudou D, Kang PB, Haslett JN, et al.  Transcriptional profile of postmortem skeletal muscle. Physiol Genomics. 2004;16:222–228

PII: S1072-7515(04)00758-6

doi: 10.1016/j.jamcollsurg.2004.04.023

Journal of the American College of Surgeons
Volume 199, Issue 3 , Pages 411-418 , September 2004

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